Modern view on rosacea: Topical issues of epidemiology, pathogenesis and therapy. Literature review

Rosacea is a multifactorial dermatological disease that widespread throughout the world, initially manifested as cosmetic defect, and in absence of systemic topical therapy leads to change structure functions facial skin.
 Patients with rosacea often seek medical attention, these aesthetic problems impair their quality life contribute development social psychological problems. Chronic stress cause maladaptation, which occurs because constant feeling self-doubt, own inferiority, anxiety. Anxiety chronic depression can even minor manifestations rosacea, it localized on skin face. Dermatosis manifests itself women older than 30 years, under influence multiple trigger factors, has relapsing course.
 Understanding pathophysiology use combined therapies improve effectiveness patients achieve prolong clinical remission, identify factors possible prevention. This explains need study not an independent dermatosis, but sign more significant disorders lead only problems, also affect general health patient.